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Margaret,
After being on Sinemet for the last 10 years with increasing dosages,
I hit a condition where I experienced over medication and the dreaded
dyskinesia or under medication with paralyzing bradykinesia.
I have been ramping up on the Permax and decreasing the Sinemet over the
last 3 weeks.  The transition has been a terrible experience. I expect the
process will take about three month before I am comfortable again.
Check with your neurodoctor about Permax.
 
Jon Stedman  <[log in to unmask]>
 
PS:  What is the meaning of the "bid" and "tid" on prescriptions?
      It's not obvious to me...