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In a reply letter Mary Ann sent me recently, she mentioned that because of her husband Jamie's, dangerously high blood pressure, he doesn't have the horrible adverse reaction to Sinement's hypotensive side effects and that perhaps that's why he's able to continue to work etc. It occurred to me then, that perhaps by adding a med to *raise* the BP of people who are on Sinemet it would elevate not only their BP but their quality of life as well??? I'm sending the following excerpts from messages between Mary Ann and me in the hope that perhaps something beneficial will come out of it. -------------------------------------------------------------------- MA>........His BP is dangerously high, which means that he doesn't have MA> the adverse reaction to Sinemet's hypotensive side effects. Perhaps MA> that is why he can continue to work. HN> When I first read what you wrote (above) it occurred to me that HN> maybe there's some medical 'tip' to be found in it. If indeed the HN> *low* BP triggered by Sinemet (and perhaps other meds?) users, HN> exacerbates the PD, perhaps *elevating* the BP would enhance HN> quality of life? Mary Ann, wouldn't it be *wonderful* if 'we're' on HN> to something? Love to hear from you re MA> I have told every doctor that we have come in contact with about MA>the exacerbation of PD that occurs when my husband takes too MA> much anti-hypertensive medication. They look at me like I'm crazy. MA> We finally have doctors that listen. MA> Sinemet plummets blood pressure. Jamies uses it as part of his MA> BP regime. Doctors are supposed to recognize that. I began to MA>appreciate Sinemet as a BP drug when I noticed that my PD patients, MA> almost without exception, had to quit work because they kept MA> passing out even though their other PD symptoms were less severe MA> than my husbands. ------------------------------------------------------------------ I hope with all my heart that perhaps there is something helpful in the above. :-) Wouldn't that be a WONDERFUL start to the New Year! Happy, Healthy New Year to All! Helen Spence ([log in to unmask])