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input for Patrick Martin survey. ------------------------------------------------------------------------ Name:Ben McKeen e-Mail:([log in to unmask]) Zipcode:05452 Age:61 Weight:140 Sex:Male Years Parkinsonian:8 Years Medication:8 Medical Indications: 1.parkinsonism (tremor, Bradykinesia, fatigue, stiffness, dyskinesia, speech problems etc Medications: NAME DOSAGE(mg X daily frequency) 1.Sinemet 25/100 X 6 2.Permax .05 x 9 3.Eldepryl 5 X 2 4.Vitamin E 400 IU x 1 5.Vitamin C 500 X 2 6.multi-vitamin x 1 7. Comments: (Comments should include, but not be limited to, your experiences with the FDA-approved drugs and alternatives such as NADH, melatonin, nutritional supplements. We are looking for both positive and negative comments since this is a unique contribution to be made to the PD literature. Your history of drug menu changes is also important. Don't forget to include your observations on adverse reactions and interactions.) 1. 8 years Parkinsonian listed above is since diagnosis. I can recall experiencing various syptoms for at least 2 years prior to diagnosis. 2. I take 1 Sinenet about every 2.5 hours during the day and taper off during the evening. 3. My neurologist had me try Sinemet CR last year but it was not nearly as effective for me as the plain Sinemet. 4. I also tried the generic equivalent of Sinemet for several months and had very unpredictable results so I waent back to the brand name medication. 5 When I'm "on" I experience some dyskinisia and when I'm "off" it's bradykinisia. There doesn't seem to be any happy medium these days. ------------------------------------------------------------------------