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Edema of ankle is common in PD - it is often in the foot or ankle on the side where PD's first symptoms started. Probably caused by slowness or lack of activity on that side. My left side is my most affected side and I get occasional edema of my left ankle which hasn't lasted more than a couple of days - untreated. I try to walk more and that helps. Some drugs such as amantadine cause leg and foot edema. Barbara Yacos <barbyac>