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More careful study of the Lees paper in the BMJ, reviewed in today's
post of Current Science Reviews, revealed a) 782 participants were
assigned in 3 groups, and only 520 were divided between levodopa alone
and levodopa plus selegiline, the rest getting bromocriptine alone,
so the numbers are consistent with the companion commentary;
b) causes of death in the first 2 groups were indeed tabulated, but
not in great detail. 44 out of 249 subjects on levodopa alone, and
76 out of 271 subjects on levodopa plus selegiline, died during the
5 to 6 years of the trial. The biggest difference was 26 of the second
group deaths assigned to "Parkinson's Disease" compared to 7 in the
first group. Deaths from "cerebrovascular disease" were 11 in the
second group vs. 2 in the first, but in "other cardiovascular
disease" the result was reversed, 1 vs. 7. Sorry for the confusion,
haste makes waste. I suggest adding this note to your file of monthly
Reviews.
 
Cheers, Joe
 
 
J. R. Bruman (818) 789-3694
3527 Cody Road
Sherman Oaks CA 91403