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Pat
        I would be interested to know the name of the neurologist running
these two trials. My father is being treated by a neuro at WUMS and has not
heard of these trials. Can you tell me what the enrollment criteria are?
Don Glaeser
 
At 03:57 PM 1/14/96 -0600, you wrote:
>Barb,
>
>I've been part of the pramipexole study at Washington University in St.
>Louis for three years.  For me, the principal benefits have been an
>improvement in balance, handwriting, and constipation.  If I'm "off" when
>I take it, I don't go on, but if I'M on, that dose seems to become more
>effective, sometimes to the point of causing dyskinesias.  I don't notice
>much effect of subsequent doses, but I might notice the difference if I
>weren't taking it.  Hope that helps.
>
>Pat Schark
>
>P.S. My neurologist is also heading the tolcapone study, and seems to
>feel that's even more effective.
>
>