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On Monday, 22 Jan 96, I winged my way to the Mayo Clinic in Rochester Minn. for a visit with my treating neurologist. My last visit was in May 1995. I was concerned about my medication schedule since I was getting wear off symptoms in the afternoon. Likewise, I was concerned about the Eldeptyl medication I have been taking for the past five years, or so. I had faxed him the posting about the UK study back on 16 Dec 95, for which he greatly appreciated and read the entire study himself. He knows Dr. Lees (involved in the study) personally and has a great deal of respect for his insight. Thus, folks I was advised to discontinue Eldepryl. He also advised me he will be discussing this medication with his movement disorder colleagues and unless there is any convincing evidence to the contrary in the discussions I will be off this medication permanently. I pass this on to the net not to cause fear but only to enlighten you of what at least one neurologist who devotes his practice to PD has, for the moment at least, has concluded. Peace to all. Jim Ryan 56/7 Medication schedule: 1 1/2 Sinemet & 1/2 Permax at 6 am, 10 am, 2 pm, 6 pm