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Alan Bonander e-mail <[log in to unmask]> Zipcode 94583 Age:55 Weight:210 Sex male Year of first symptom: 1977 Year diagnosed: 1984 Year started medication: 1984 Medical Indications 1 parkinsonism-idiopathic 2 asthma Medications NAME DOSAGE (MG x DAILY FREQUENCY Eldepryl 05 x 1 Paxil 20 x 1 Sinemet 25/100 x 1 Liquid Sinemet Levodopa 49.5 mg / hr 800 mg / day Carbidopa 6.75 mg / hr 108 mg / day Permax 0.12 mg / hr 1.92 mg / day Vitamin C 4000 mg Vitamin B6 50 mg everyother day Melatonin 6 mg as needed Comments: I was started on Sinemet 25/250 x 4 daily. I tried Parlodel but found it was not effective The end of the honeymoon with Sinemet was in 1988. Almost everything wouuld cause problems. Sweating, dyskinesia, tremor, bradykinesia and rigidity were problem symptoms. In May of 1991 participated in research on duodenal infusion. I have been pumping liquid sinemet ever since This stabilized response, added predictability to response and I learned a lot about PD and medications. May of 1993 traveled to Stockholm, Sweden for Right Pallidotomy. Results are 95% of rigidity gone in left leg, 50% of rigidity gone in left arm, better facial expression, wider theraputic window. Current issues: Problems with sleep, food, depression, swallowing, asthma--PD. All are being treated but not necessarily solved. I can shut down ver y quickly from food. To help get around some of these problems, I wll take about 50 mg of levodopa (liquid sinemet) as I start lunh. This will avoid OFF time after lunch. For evening meal I will take 100 mg of levodopa (liquid sinemet) at the start of thee meal. This will avoid the 7 to 9 pm OFF time. I consider these doses wasted medications and do not count them in my normal meds. I iwll use these wasted meds about thrree or four times a week. Regards, Alan Bonander