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This is a corrected set of data. Please ignore previous post. Alan Bonander e-mail <[log in to unmask]> Zip code 94583 Age:55 Weight:210 Sex male Year of first symptom: 1977 Year diagnosed: 1984 Year started medication: 1984 Medical Indications 1 parkinsonism-idiopathic 2 asthma Medications NAME DOSAGE (MG x DAILY FREQUENCY Eldepryl 5 x 1 first thing in the morning Paxil 20 x 1 first thing in the morning Sinemet 25/100 x 1 first thing in the morning Liquid Sinemet Hourly 16 hour day Levodopa 49.5 mg 800 mg Carbidopa 6.75 mg 108 mg Permax 0.12 mg 1.92 mg Vitamin C 4000 mg Vitamin B6 50 mg every other day just before bedtime Melatonin 6 mg as needed Comments: I was started on Sinemet 25/250 x 4-5 daily. I tried Parlodel but found it was not effective The end of the honeymoon with Sinemet was in 1988. Almost everything would cause problems. Sweating, dyskinesia, tremor, bradykinesia and rigidity were problem symptoms. I had problems with diphasic dyskinesia. ON time was about 2 hours a day. In May of 1991 participated in research on duodenal infusion. I have been pumping liquid Sinemet ever since This stabilized response, added predictability to response and I learned a lot about PD and medications. May of 1993 traveled to Stockholm, Sweden for Right Pallidotomy. Results are 95% of rigidity gone in left leg, 50% of rigidity gone in left arm, better facial expression, wider therapeutic window. Current issues: Problems with sleep, food, depression, swallowing, asthma--PD. All are being treated but not necessarily solved. I can shut down very quickly from food. To help get around some of these problems, I will take about 50 mg of levodopa (liquid Sinemet) as I start lunch. This will avoid OFF time after lunch. For evening meal I will take 100 mg of levodopa (liquid Sinemet) at the start of the meal. This will avoid the 7 pm to 9 pm OFF time. I consider these doses wasted medications and do not count them in my normal meds. I will use these wasted meds about three or four times a week. Regards, Alan Bonander Age 55, Diag 12 yrs, liquid meds, pallidotomy [log in to unmask]