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>Sinemet is the trade name for a series of drugs combining L-dopa and >carbi-dopa which are generic names for two dopamines. L-dopa is an amino >acid normally manufactured by the body and residing in the brain. > Interference in the body's manufacture of L-dopa resulting in a deficienc= y > in the brain cells causes Parkinson Disease (PD). Therapy for PD normal= ly >consists of replenishing the missing amino acid with a synthetic L-dopa. Thank you all for your answers, do you know the indication for Sinemet (L-dopa and carbi-dopa)? My mother is under medical treatment with Madopar=AE (L-dopa and benzerazid) and Bromocriptin only. She is suffering with PD since 10 years. Her neuro says, she has an "one-side parkinson disease". She is hard to treat because the drugs are good for the sick side (right arm and leg) but at the left side she is suffering with uncontrollable convulsion and spasm. She has a very low dose therapy (62,6 mg L-dopa/die). What do you think about it? Bye, Matthias M. Schaefgen, Buchseifen 36, D- 57072 Siegen, phone: 0271/3757300 MacNet: Matthias Schaefgen,Siegen OnLine [log in to unmask]