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Barbara Y said .."I have read that patients on Sinemet (carbidopa/levadopa) should take at least enough to assure getting at least 75 mg carbidopa and up to 150 mg daily (24 hours). One guide says 100 mg is all most people need. You said target is around 100-150 mg. So it looks like we all agree on something like - no less than 75 mg and no more than 200 mg carbidopa (in Sinemet) daily." This interests me from the 'other end'....Clyde is currently taking 10/100 Sinamet (3x day)...does this mean he may be getting enough Carbidopa??