Terry Brennen Here are my answers to your questions: 1. Would pallidotomy harm a non-PD person? It is my understanding that the location of the lesion in the pallidotomy is in an area that should have little or no activity. Creating the lesion should not be a concern if this is he case. Just a comment on YOPD. It is true that we will have PD longer than normal or late onset, but you must realize that progression in YOPD is slower. Other differences are YOPD usually has dyskinesia where this is of a lesser concern for others. YOPD is less likely to have mental problems like hallucations,etc. In any case the road is not smooth. 2. Ten years ago YOPD was considered rare and often misdiagnosed. Today there are many with YOPD. As a result at least the larger medical facilities will have a good understanding of PD in the young. As one neruologist told me years ago, his skills are in treating his patients. If you don't have a patient with disease X, the neurologist has only a passing interest in that disease. 3, I live on the West Coast where we are watching the flowers bloom and enjoying temps in the upper 70s. Someone else can answer this. 4. DHEA - I will also beg off this question Regards, Alan Bonander [log in to unmask] San Francisco Bay Area