Joe Bruman Wishing to know more about the geography of the brain and how it all fits together launched me upon my own independent study of the neuroanatomy of the brain. Based on my study I would offer the following in response to your query. Fetal cell transplants are placed in the striatum never in the substantia nigra. The striatum is a sub-category of the basal ganglia. The striatum includes the putamen, caudate nucleus and the nucleus accumbens. The basal ganglia meanwhile includes the striatum plus the globus pallidus. The thalamus lies medial (toward the center of the brain) and ventral (below) the caudate nucleus). The putamen lies lateral (toward the outside of the brain) and ventral to the caudate nucleus. The globus pallidus (site of a Pallidotomy ) lies ventral to both the putamen and the caudate nucleus. The substantia nigra as part of the midbrain along with the red nucleus and the reticular formation lies ventral (beneath) the basal ganglia and dorsal (above) the pons and medulla oblongta. The best suggestion I could make would be to get yourself a book on neuroanatomy and draw pictures representing where the various parts of the brain lie in relationship to one another. There are also plastic life--size models available by which you can take the brain apart and see exactly where one part is in relationship to another. They are very expensive however, like $400. Don Dr. Don Berns 4943 Del Monte Rd. La Canada, CA 91011 818-790-8812 <[log in to unmask]>