Deanna, My wife, who probably has "Parkinson's Plus," and after only 6 years is totally dependent upon others, has taken Pamelor (10 mg, 3 capsules per day) for several years. It has always seemed to help and has not been addictive, nor are there any apparent side effects. However, I tend to agree with your overall assessment of depression medications. I think that good family care is the best medicine for the mental well-being of the patient. Beware of serious psychological problems that can suddenly arise when the patient is over-medicated. Porter Humphrey