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From: Brian Symonds <[log in to unmask]> Hello Jeannette I read your note about your father-in-law, his PD, his chest pain, and his reaction to Morphine. I am not aware of any reaction to Morphine peculiar to PD that might cause his symptoms. Morphine on its own can cause such a reaction, even in those without PD.It is unclear if his symptoms are part of a "delirium", or part of a "psychosis" (both medical terms with specific meanings).Each of these conditions is treated differently. There are other pain medications, and someone (perhaps you or your husband) should talk to his family doctor and insist that a note be put on his hospital chart that he is not to get Morphine, and, if necessary in emergency, insisting that he is "allergic" to it (although that is not medically true) and that he can't have it. However, it is possible that if one narcotic has caused this, others (such as Demerol or Meperidine) will also do the same. And, if he is on Deprenyl, he cannot take Demerol. The basic problem would be to try to determine the cause of the pain, and treat that rather than the pain itself. It may take some testing to try to determine the cause of the pain, and he will have to be prepared to go through the tests. If the pain is not from his heart, then it may be from his esophagus or stomache or gallbladder or colon or a musculoskeletal pain or even from tension. The Powell River Parkinson's Support Group have a booklet about Parkinson's Disease, and if you would like a copy, send me your snail mail address.There is also I understand a good Parkinson's Group in Victoria.