At 08:12 PM 3/21/96 -0500, you wrote: >Some friends have asked for more information on apomorphine. They've heard >that it is highly effective in reducing dyskinesias common with long term >l-dopa usage. This is not a question about the short-acting pen-injection >studies to relieve freezing, but more about regular long-term administration. >My last PD Digest references on apomorphine are from late 1994. Is anyone in >Europe or Canada using apomorphine on a regular basis to substitute for >sinemet and getting relief from dyskinesia? > I have chatted with a nurse in the UK on the Parkinson's chat and it was her opinion that apomorphine was a poor substitute for carbidopa/levodopa. I believe that her opinion was based on 'quality of life' observations. Apomorphine is being tested in Canada as a solution for impotence in Parkinson's disease and apomorphine is also being tested there in tablet form. One thing is clear, presently it will 'rescue' those frozen while crossing a street....It allows one to continue on to the otherside so that one can vomit in safety. Domperidone is used with it to reduce this side-effect. John Cottingham "The parkinsn list brings Knowledge, Comfort, Hope, and Homeboy Friendship to the parkinsonian world." LibraryH Parkinson's Chat on the Undernet 8:30 PM CST -6 Daily. If you access the Internet through a provider with a [log in to unmask] PPP/SLIP account, free IRC chat software is available. WFD