Apomorphine was described as- ...presently it will rescue those frozen while crossing the street ... it allows one to continue to the other side so that one can vomit in safety. Domperidone is used to reduce this side effect. I have been taking apomorphine infrequently for two years. The first few doses were unpleasant but domperidone soon proved very effective in suppressing nausea. More importantly, I have recently found that I do not need domperidone and can take an injection of apomorphine to get out of a difficult situation at any time. This aclimatisation to apomorphine seems to persist even if I don't use it for several weeks. Having apomorphine on hand has given me the freedom to do many things that would otherwise be too risky. I hope others will not be discouraged by the reputed side effects. I certainly would not like to be without it. Nigel Cockle 51/12