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Gordon and I wondered why you are taking Sinemet CR and another Sinemet prescription at once. Also, could you change back to the medication you took before and drop the new one? Do one at a time, of course. At 11:57 AM 4/4/96 -0500, you wrote: > We are at a low point now and have been there for about 6 weeks. Nancy >had > been progressing beatifully since her unilateral pallidotomies last >May > and July. We have been adjusting and changing meds in an attempt to >get as > much benefit out of the surgery as possible, but we have managed to >get > into trouble. After successfully using Prozac to contol depression for > nearly 7 years, we decided to try Serzone. As has been reported here >it is > supposed to have fewer side effects than Prozac including less impact >on > sleep disorders and sexual function. > > At this crossroad depression is contolling our lives. Neither of us >are > getting much sleep. Nancy is hyperactive, compulsive and crys easily >but > only briefly (1 or 2 minutes per episode). PD off periods are awful. > Freezing and akinesia are potent and long lasting (one to two hours at >a > time). PD meds seem to be working but the results aren't normal. For > example the standard tests of elbow and wrist mobility almost always >are > asymptomatic or slightly rigid but right side back muscles are >dystonic > and legs just don't want to move. There is no return of dyskinesia > (pallidotomy seems to have eliminated it for good - we hope) but this > depression and freezing is making us pay a heavy toll. > >Current meds follow: >Medicine frequency quantity daily total >Serzone 100mg. 9am & 1pm 1 200mg >Sinemet 25/100 every 1 1/2 hr. 1 250/1000 >Sinemet 25/100cr every 3 hr. 1 100/400 >Permax 1mg every 1 1/2 hr. 1/2 4mg >Ativan as needed taking 1 or two a day >for anxiety >Klonopin .5mg at night occasional use for sleep >Trazodone 100mg at night occasional use for sleep > > Nancy is 51, PD 20 years > > Looking for comments from any who are taking Serzone. > > 1. How many milligrams per day? > 2. How long did it take to see the benefits? > 3. Have you noticed any changes in the way your other PD meds are >working? > > We are seeing a neurologist, psychiatrist (for the serzone) and >getting > counseling to get us through this period but without much success. Any > ideas/thoughts/help would be appreciated. > > --------------------------------- > Bob Martone [log in to unmask] > --------------------------------- > >