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Has anyone been on Sinemet and Prednisone at the same time? I was in sad shape, unable to stand unassisted and my right arm was almost useless. When I went on Prednisone for a serious allergic reaction, miraculously the unstableness in standing and the inability to use my arm were gone. When I stopped the Prednisone the symptons reappeared. The two therapists that were treating me were amazed. I would like any imput from people that have had similiar or dissimiliar reactions.