Hi: I wonder if anyone else has tried the herb Ginkgo to relieve some of the side effects of Permax. Permax (although I am on a very mild dose) was making my limbs very cold, leaving me confused and depressing my mood. My MD said that the cold limbs resulted from Permax's tendency to constrict blood vessels. I noticed in a herbal book that Gingko dilates blood vessels and improves circulation so I decided to give it a try. Maybe its my imagination, but 4 weeks later ALL of the side effects have been noticably reduced. Maybe I'm coincidentally going through a "good" phase. I can't tell for sure since I'm still new at this. But those of you suffering these side effects may want to try Gingko. I bought it in capsule form at a local nutrition center. The bottle says that it takes a few weeks to kick in, so be patient (no pun intended). Incidentally, I am on Permax and Eldepryl. Also I've added B6 for color. Actually I remember reading somewhere that B6 sometimes helps other vitamins and supplements to work better. Ron Reiner 48 + 7mos PD and counting ([log in to unmask])