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Welcome, Ernie, to this panel of your Peers ! We hope both you and your wife, , will remain " on board." I printed your posting - my husband and I digested it at breakfast. 1 Stress can reduce the effect of our medication: (as I understand it) the adrenal glands react to stress - fight or flight adrenals release acetylcholine acetylcholine interferes with dopamine release.( general conception - I'm no expert). 2 Eldepryl weaning. I plan to talk it over with my neurologist....not because of the mortality study (which is being questioned by Peer Reviewers of several journals), but because of its (Eldepryl's) adverse interaction with medications necessary for surgical procedures. Have had two unpleasant experiences taking less than adequate pain killers. Would investigate going "Off" Eldepryl two weeks before future surgery, if possible. Stay on board! [log in to unmask] (Mary Manfredi)