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Hi, My mother (Pam Barnett) has PD, and has been adjusting sinemet dosage (now taken in liquid form) for sometime to help ridigity, tremor, etc. (She doesn't think she gets dyskensia yet). She gets mixed results from the medication, no effect sometimes, and better results on low protein diet. We read your email on the PD List, summarising how you improved your wife's regime by calculating the levadopa concentration in the bloodstream over the day, to determine acceptable min and max levels. I would be very interested in the levadopa/bloodstream figures that you used. Could you send them to me and/or a reference. Also, what about other factors that possibly effect the uptake of levadopa (Diet, Stress, Activity, Liquid or Pill form, etc). Are these averaged figures and do they indicate the variance. Just wondering how much these figures vary for different people. Regards, Kim Barnett for Pam Barnett (63 PD 9) [log in to unmask]