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Hi Kathie I'm glad you're addressing the special effects of PD on younger women. I go through the same horror - not every month, but about 8 out of 12! I was prescribed Acetazolamide 250 mg, 1 tablet 3 x day, 10 days before mensus. It seemed to work at first, then didn't. Very soon after starting this med, started seeing double and constantly seeing silver circles at the two sides left and right. My doctor said the medication was something given to persons with Epilepsy, and they didn't understand how it works, but somehow it helps some premenopausal women parkies soften that horrible time. Doctor explained the silver circles as something to do with the nerves reacting to the medicine. I took it for several months, but the times of horror kept running into more and more days causing and I was told my PD's progression was the culprit. So the meds were discontinued.