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-- [ From: Donna Kipp * EMC.Ver #2.10P ] -- Pam,After seeing this article and observing generally younger women do better then younger men with PD. I spoke with my neuro and asked him if estrogen may be a factor and he agreed with the observation and thought it was possible. I am planning on going on ERT in the next month or so. I went on it a couple years ago and noticed it made my PD symptoms worse. As usual this is an ambiguous situation....... Donna