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Date: Fri, 19 Apr 96 10:07:36 -0500
To: Robert B Howard <[log in to unmask]>
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From: "Robert B. Howard" <[log in to unmask]>
To: [log in to unmask]
Subject: Re: Sinemet?
Message-Id: <[log in to unmask]>
Date: Fri, 19 Apr 96 10:07:36 -0500
In message <[log in to unmask]> Parkinson's Disease -
Information Exchange Network utoronto.ca writes:
> I have not been able to resolve the question about the efficacy of Sinemet
> over time. It has been stated that the administration of Sinemet should be
> delayed as long as possible so as to defer the eventual loss of effectiveness
> of the drug.
> Question:
> (1) Is this loss of efficacy due to built up immunity against the drug over a
> span of five or so years? Or
> (2) the drug becomes ineffectual because of the advance of the disease so
> that nothing would help at that point?
> (3) If Sinemet is initiated at a likewise advanced stage of PD, would it be
> efficatious at all?
>
> I am still baffled by the complexities of this disease. And we do the best
> we can because we do not like the alternative!!!
>
> Michel
> Near where the cherry trees recently blossomed, and
> where some idiots have for years tried to bloom on the hill.
Michel - We are all baffled by this cruel and mysterious disease. In re time to
start Sinemet: At one point it was thought that Sinemet should be delayed as
long as possible, that while it helped the symptoms, it hastened the disease
process . Current thought, however, mainly contradicts that notion, and careful
studies seem to show no hastening of the disease. I believe that most
authorities now advocate using Sinemet when one needs it.
Good luck! Bob Howard
Bob Howard, occasionally known formally as:
Robert B. Howard <[log in to unmask]>
1320 Wisconsin St.
Hudson, WI 54016
Voice phone (714) 386 3596
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Bob Howard, occasionally known formally as:
Robert B. Howard <[log in to unmask]>
1320 Wisconsin St.
Hudson, WI 54016
Voice phone (714) 386 3596
