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The PDR article on Demerol doesn't specify the mechanism, but describes the severe and sometimes fatal reactions (with any MAO inhibitor, not just Eldepryl). Cheers, Joe J. R. Bruman (818) 789-3694 3527 Cody Road Sherman Oaks CA 91403 On Tue, 30 Apr 1996, Steven E. Mayer wrote: > I know I've read a bunch of times that Demerol and Eldepryl are not to be > taken together. Why? What happens? > > My Dad fell yesterday, and badly bruised his hip. While in the Emerg. Room, > he was given a shot of Demerol. He became argumentative, combative, and "he > was leaving that place!" Was that the "normal" reaction of those two drugs? > Or was something else going on? > > Thanks, all! > > Diane > > [log in to unmask] > > Steven E. Mayer, Ph.D. >