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J. R. Bruman (818) 789-3694 3527 Cody Road Sherman Oaks CA 91403 ---------- Forwarded message ---------- Date: Sun, 5 May 1996 15:49:00 -0700 (PDT) From: J.R. Bruman <[log in to unmask]> To: "Linda S. Breedlove" <[log in to unmask]> Subject: Re: Sinemet high Linda, good question. I have read that dopamine is the addictive agent in both cocaine and tobacco (not nicotine). I've also done a little reading about differential diagnosis of PD mimics (perhaps you saw my posting) and, although the experts don't say so, response of motor symptoms to dopamine replenishment is probably the most reliable indicator of PD. If it is PD, you're lucky, the others are much less treatable by anything. Cheers, Joe J. R. Bruman (818) 789-3694 3527 Cody Road Sherman Oaks CA 91403 On Sun, 5 May 1996, Linda S. Breedlove wrote: > > I'm responding for my husband, but I can emphatically answer "Yes!" -- he > does experience this; in fact, he jokingly calls it his "heroin". > > I would pose an interesting question, however, since I really question > his Parkinson's diagnosis anyway: IF the doctor is wrong, and IF he has > something else, what would the effect of a dose of Simimet be on a brain > that is NOT deficient in dopamine? Would it act as a stimulant? > Sometimes he almost behaves as I think I used to do years ago when I took > some amphetamines for a while...it was very very intersting to see your > observation of this. Good luck to you! >