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Dear Margaret, As requested, my responses are: 1. total hrs awake = 18-19 2. total hrs nap during day = 0 3. total hrs un-interrupted sleep during night = 5-6 4. total hrs "on" on a good day = 14 5. total hrs "on" on a bad day = 10 6. average length of time for meds. to kick in = 90mins (2hrs on a bad day) 7. when in an "off" period, do you persist and attempt to remain "active" = yes 8. = Frustration, sometimes depression, (and can trigger over-reaction and mini flare-ups but thankfully not that often) dz 2.5 yrs at age 50. sinemet CR 50/200 at 8am and 5pm, with half sinemet CR at midday. Regards, Ernie Peters ([log in to unmask])