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Would appreciate any advise re use of artane vs. amantadine for early PD treatment. I've tryed low dose(2 mg per day in two half doses, am & noon) of artane for about 9 months which gave good relief from stiffness and tremor but had unpleasant effect on short term memory. Have recently switched to amantadine (2 x100 mg) as experiment. After 30 days I find it also gives good relief but w/o nasty side effects, so far. My question is, given a choice, is there any benefit to one drug vs the other as regards a person's ability to prolong time before need for Sinemet? How long is it possible to use amantadine or artane alone as treatment? BTW I also take 5mg eldepryl in a.m.-as well as NADH and various vitamins and herbs. Any comments from folks who know would be most appreciated. Thanks. Fred Schaffert (53/1)