Ihad poorreaction to Eldepryl's recommended 10 mg.dose (dizzy/orthostatic hypotension/tripping) but managed to regulate it at 2.5mg twice a day skipping day occasionaly. Eldepryl helped in that I was able to cut down Sinemet dose at the time (1989).and I was more cheerful and better able to cope. Now in preparation for surgery.I stopped Eldepryl on April 15 .a little early perhaps, but date of operation was uncertain. For three or four days I didn't miss it noticeabl.;...Then the Sinemet began to wear off much earlier; my feet bumped into each other, and I started to shuffle again. Dyskinesia worsened and dystonia became more painful The Sinemet invariably put me to sleep. I sorely missed my Eldypryl ...at least .it helped me concentrate...Surely by some mechanism, other than just raising the spirits, it helps neurologically. I can barely wait to retrieve it. [log in to unmask] (Mary Manfredi) I can barely wait to retrieve it.