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>If you gave a normal person levodopa would he develop schizophrenia? >[log in to unmask] > According to the University of Miami and my Neurologist in Sunrise, Florida---No. If there is nothing wrong with your Substantia Nigra your brain will not absorb Sinemet. I had asked the same thing, as I had 2 different Neurologist treat me and almost kill me with one dose of mysoline, 50 mg. and at an earlier time, Tedretol.200 mg. which they started out very slowly, but before I reached full strength I couldn't get out of bed, retained urine for 16 to 20 hours at a time and lost all my skin, just as I did with Eldepryl. In fact, I refused to take the Sinemet 25/100 for 3 days, as I JUST KNEW it was going to do the same thing again!!!! WRONG!!!! I felt after about 1.5 hours, so euphoric, I wanted to kick myself for waiting so long to take it. The only thing--the 25/100 did a spin, crash and burn with me if I don't get them taken on time. That was why they switched me over to Sinemet CR. My neurologist up here said CR's had a tendency to be unstable ,but the Head of Neurology at the Un. of Miami said it was an individual thing---Boy, was he right. I feel very fortunate that I live in Florida as we have some of the best Doctors in the World here. Our weather attracts them!!! However, I'm speaking of a 5 year span of time here, and when I get to feeling sorry for myself, I wish I could have developed something that the Doctors REALLY understand!!!!! Its not that they don't know--its just that they have no idea how it will react individually. **************************************************************************** ****************************************** Prayer of the Sioux Indian: "Great Spirit, help me never to judge another until I have wallked two weeks in his moccasins" **************************************************************************** ********************************************* Blessings to all, Marjorie L. Moorefield just another librarain [log in to unmask] Internet Communications of America, Inc.