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Tonight on Public Broadcasting System there was a program on the "New Explorers" series, which covers scientific discoveries. It featured a neurosurgeon/scientist ,Dr. Keith Black, who has apparently found a way to get through the netwoork of capillaries in the brain, the BBB, and "open" it briefly so a substance can be injected into a brain tumor. Not only was this fascinating in itself, but this was the first time I really knew what the BBB is, after hearing so much about it in connection with PD and problems of delivering our meds. I wonder, of course, whether this breakthrou gh will have any possible significance in relation to PD? If anyone has any info on the subject, please post it. The BBB is the brain's defense against toxins, etc., but also prevents the tumor-zapping drugs from reach- ing the tumor--hence the importance of Dr. Black's discovery, which is now going into phase 2 trials, apparently, since the safetyphase is past, and there seems to be evidence the tumors are reached in this way. The substance that Dr.Black used is called RMP-7, BTW. Could this have any possible PD application, I wonder?Deliver dopa to the sub.nigra??? Camilla Flintermann,CG for Peter,78/6+ Oxford,OH