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Dora, Thanks for the reply. I also know STRESS has alot to do with it, but it's like the depression-which came first, the depression or the PD? Which came first, the nausea or the PD? My neurologist has given me LODOSYN to take with the Sinemet. Do you know anything about this medicine? It seems to have helped the nausea but I hate to take more drugs. I have had others tell me about not breaking the Sinemet in two, I'll have to ask the Dr. Crackers and juice have helped me also. Thanks, Patricia 59, one year plus