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> Interesting. I am wondering still if the category "milk" is not specific enough. There is knowledge that fat is digestively in the stomach longest, protein next. How much of the "milk problem of interference" is> digestive residence metabolic loss (= digestion) of the levodopa while held> in the stomach?> In other words, is the major loss in the stomach or in the LNAA absorption> from the small intestine? I suppose the levodopa percentage leaving the> stomach could be much dependent upon the individual's digestive modus > operandi. Well, good point. Since levodopa has a short half life, high-fat food such as whole milk would certainly delay stomach emptying time and keep the med from getting into the intestine. Also, stomach enzymes would have more time to go to work on the early stages of metabolizing the med. And that would lead to lessened absorption of the med. However, assuming use of nonfat or skim milk, fat would not be a factor unless other foods were taken with the milk and med. A glass of milk has relatively little protein (though more LNAAs, proportionately, than meat), so I wouldn't have thought protein would be a factor either. I'm wondering if it might be some other factor unique to milk --the casein, lactose, etc. -- that affects some people but not others. -- Kathrynne Holden, MS, RD Editor-in-Chief, "Spotlight on Food--nutrition news for people 60-plus" Tel: 970-493-6532 Fax: 970-493-6538 http://www.fortnet.org/~fivstar Contact Better Business Bureau of the Mountain States, < [log in to unmask]>