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Dear Joyce, We sympathize with your frustration. Dave (pallidotomy 4/94) at Loma Linda, also takes Hydergine (Dr. Iaconos special RX for P;, and NADH. No neurologist has approved his taking the hydergine, but his on/off, balance, and freezing are diminished with it. RE NADH, I think his energy level has increased. Please write via email, for more infor, if you wish. Good luck, dave n lyn (LYnne)