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I called Dr. Gash at the University of Ky. last month concerning his research
with GDNF (glial-cell-line-derived neurotrophic factor). His office referred me
to AMGEN Inc. in California where the substance was originally discovered. I
spoke to a clinician there about whether a pallidotomy would jeopardize
anyfuture use of growth factor on a post-pallidotomy patient. Her response was
that their research to date has not included the use of this growth factor on
MPTT treated primates that have had a pallidotomy.  So, we have learned nothing
about whether or not a pallidotomy will risk any future use of neuro-growth
factors. This has been a concern to me since I am trying to make the decision
whether or not to have the operation. Any comments?


                                    Claude Dungan ([log in to unmask])