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Steven, I read with great interest your recent post re NADH. I've been trying NADH for some months now and have had good results but I also share your concerns about the hype and price of the product. While I don't have the knowledge and experience with NADH that you have, I would like to make the following comments regarding the points you made. 1) Regarding absorption from oral doses, Birkmayer of Austria, who seems to be the main proponent of this therapy, published some articles which claim that oral administration was quite effective for his patients-as effective as intravenous injections. 2) Birkmayer has published a number of articles in foreign medical journals describing his work with NADH. 3) The price is outrageously high, but at $69 for 30x5mg-the price obtainable from Lisa Carper's pharmacist in PA, I calculate the price to be $11.50 per 25 mg not $100.00 as you stated. The new price from Life Extension in Florida is $24 for 30x5mg (with 25% member's discount) or $4.00 per 25 mg. Menuco Corp. claims a U.S. patent(5,332,727) for their form of NADH which they call "Enada". The source of Life Extension's at the new lower price is unknown to me. Could this patented form be more effective than normal NADH? Without further tests, the answers to many of our questions are just not available now. I am skeptical too, but its hard to ignore Birkmayer's work in Austria with hundreds of PD patients especially when one obtains therapuetic effects on an individual trial basis. What's a new PD patient to do? Further comments on this subject would be most appreciated. Regards to all, Fred Schaffert (53/1)