Print

Print


I just read of yet other research in a Northwestern University alumni
publication which is in progress and has potentially great significance for
degenerative nerve cell disorders like Alzheimer's and Parkinson's work.
Researchers in the lab of William Klein, professor of neurobiology and
physiology, have been tracing the path of the "A Beta" peptide, a fragment of
protein that becomes toxic in diseased nerve cells.  Evidence has been
growing that that it may be an agent (rather than a by-product) of nerve cell
destruction.  In October 1994  "Journal of Biological Chemistry" Klein et al
suggest that it corrupts "signal transduction pathways implicated in diverse
cell functions...Specifying the toxic effects of the peptide makes it likely
that a drug  target for nerve degeneration can be found."
Additional research since '94 has further expanded and supported this thesis.

Another sign of hope,
Barbara Blake-Krebs
[log in to unmask]