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[log in to unmask] wrote: >=20 > My mother has fallen in the nursing home and broken her hip. I am conc= erned about drug > interactions. They are giving her Darvocet for pain. Will that make h= er > dementia worse? She is presently on Sinemet, Sinemet CR, Permax, Amant= adine, > and Trazodone. (She also takes Synthroid, Colace and Vitamin E.) ------= ------------------------ Pam, Here's a report on the drugs you listed, please let me know if this is=20 of any help to you -- =9AAcetaminophen (Tylenol=AE) =9AAmantadine (Symmetrel=AE) =9ADocusate (Colace=AE, Surfak=AE) =9ALevodopa; Carbidopa (Sinemet=AE) =9ALevothyroxine (Synthroid=AE, Levothroid=AE, Levoxyl=AE) =9APergolide (Permax=AE) =9ATrazodone (Desyrel=AE) 6 of these drugs may cause: =95nausea/vomiting (acetaminophen; amantadine; levodopa/carbidopa;=20 levothyroxine; pergolide; trazodone) 4 of these drugs may cause: =95diarrhea (amantadine; docusate; levothyroxine; pergolide) =95orthostatic hypotension (amantadine; levodopa/carbidopa; pergolide;=20 trazodone) 3 of these drugs may cause: =95abdominal pain (acetaminophen; docusate; pergolide) =95anorexia (amantadine; levodopa/carbidopa; levothyroxine) =95dizziness (amantadine; pergolide; trazodone) =95drowsiness (amantadine; pergolide; trazodone) =95headache (amantadine; levothyroxine; trazodone) =95insomnia (amantadine; levothyroxine; pergolide) =95tremor (levodopa/carbidopa; levothyroxine; trazodone) =95weight loss (levodopa/carbidopa; levothyroxine; pergolide) =95xerostomia (amantadine; pergolide; trazodone) 2 of these drugs may cause: =95anxiety (amantadine; pergolide) =95ataxia (amantadine; levodopa/carbidopa) =95constipation (amantadine; pergolide) =95dystonia (levodopa/carbidopa; pergolide) =95fatigue (amantadine; trazodone) =95fever (levothyroxine; pergolide) =95hallucinations (amantadine; pergolide) =95heart failure (amantadine; levothyroxine) =95hypertension (levodopa/carbidopa; pergolide) =95hypotension (pergolide; trazodone) =95involuntary movements (levodopa/carbidopa; pergolide) =95irritability (amantadine; levothyroxine) =95leukopenia (acetaminophen; levodopa/carbidopa) =95neuroleptic malignant syndrome (amantadine; levodopa/carbidopa) =95palpitations (levothyroxine; pergolide) =95psychosis (levodopa/carbidopa; pergolide) --=20 Kathrynne Holden, MS, RD Editor-in-Chief, "Spotlight on Food--nutrition news for people 60-plus" Tel: 970-493-6532 Fax: 970-493-6538=20 http://www.fortnet.org/~fivstar You may wish to contact: Better Business Bureau of the Mountain States, < [log in to unmask]> for further information.