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> If, however, he is using Sinemet and does experience some off times, > then she may wish to adjust the timing of the Ensure. One can of Ensure > contains about 9 grams of protein, two grams of which are the large > neutral amino acids that interfere with Sinemet absorption. In this > case, it would be best to give him the Sinemet 30-60 minutes before > administering the Ensure. I am a PD sufferer, and am trying to continue working. I have on/off times which I find difficult to govern. I have been following this thread with interest, therefore. There is little reliable information available in our small town (pop. 30,000). In an area of the Web on alternative medecine, I saw a claim that the amino acids L-TYROSINE and L-GLUTAMATE were beneficial to PD sufferers, in that they aided the uptake of l-dopa. In view of your comments about "... large neutral amino acids...", could you comment on this. (I know nothing of the subject.) Jim