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just watched my husband change from a fairly normally functioning man into one who is shaking violently and quickly becomming immobile. Why? He was trying to settle a thorny problem with a health provider on the phone. We have learned to try for maximum tranquillity in our lives these days. I believe the reason for this is the way the body utilizes dopamine. The normal source of dopamine is the amino acid, Tyrosine. Dopamine, in addition to its function as a neurotransmitter, is the source of adrenaline in the human body. One dopamine pathway is to produce norepinephrine, which is, in turn, converted to epinephrine -- or adrenalin. It is no wonder that those with limited dopamine available cannot tolerate stress, for it seems the "fight or flight" response competes with the neurotransmitter function. In another pathway, dopamine is the source of melanin in the body. This has made me wary about taking any of those related melatonin products without more information. We do enjoy reading your messages, Jim. Martha Rohrer [log in to unmask]