I have a very specific question to ask the nutritionists on the list. My sisters have been staying with my Mom and Dad this summer and doing some experimentation with the meds to a) minimize the dementia to avoid using clozaril, and b) optimize the sinemet and amantadine to avoid freeze-up times. Dad is totally tube fed. IN addition to PD, he has a esophageal ulcer and a stomach ulcer. SO, the prescription is to give him his carafate by tube one hour before his meds and Ensure Plus. In trying to adjust to the protein information from Kathrynne Holden - our questions is Should we give him his meds WITH the carafate, or the carafate, wait 1/2 hour, then meds, wait 1/2 hour and then Ensure? Or what other recommendation can anyone give? We are surely believers in the protein interaction theory. Last week the Ensure provider sent a case of SUstacal - telling my mother that they were the same. Dad was considerably stiffer and did poorly for two days until my sister read the labels and found that not only was the calorie count lower, but the protein was 65% more - and it was inappropriate for Dad as a complete nutritional substitute. I would sincerely appreciate any input! Sara Byron daughter of Richard Byron, 79/ PD since '69