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Thanks, Margaret Tuchman, for your reply to my message about tylenol. In it you also mentioned Pseudoephedrine. My story about pseudoephedrine, not related to PD, it should warn everybody, whether you're already taking meds or not, to be careful. Since we live in an area with a lot of pollen, dust, mold, etc, allergies and sinus trouble are very common here. The first time I had a reaction to sudafed was right after I graduated college, and was working at my very first "real" job. I was sent home from work for acting "weird". Clearly it was a med reaction and luckily I was not penalized for this. But it took a couple more years before I actually realized what was doing it. On that occasion, I had the most bizarre feelings that things were crawling on me, and that somebody had cut my head open and poured alkaseltser around my brain (that's how I felt, like something was bubbling in my head!) After discussing this with my brother in law who was a practising pharmacist at the time, he advised me against sudafed because it is "psychoactive" in a very small percent of the population. The last time I had sudafed, after specifically warning the dr. against giving it to me, I had to attend a wedding. Not only was I too drunk to drive, and thought it was funny that my car was weaving all over the road, at the wedding I thought the father of the bride was Charles Manson! So, anybody can have a bad reaction to drugs, not just PD patients. The only thing that finally saved me from any more bad experiences with sudafed is that I told my pharmacist. They've saved me from getting sudafed again on several occasions. The point is, dr's can't always remember which drug has pseudoephedrine & which has the other one (phenyl something or other). If you have a problem with a specific drug, you might get better results by telling your pharmacist to help you watch out for it than trying to tell the dr. Hopes this helps somebody out there. I'd hate to have any of you think your cousin's ex husband was Charles Manson! Vicki Peyton [log in to unmask] Vicki