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To Gilbert and Ron - I have had two different episodes of red patches and this is what I learned. 1) amantadine (symmetrel) can cause a purple-red mottling of the skin on legs and feet. There is no change in the skin's surface. With me it accompanied a swelling in knees and ankles which made my arthritis worse. When I stopped amantadine to find out whether the knee swelling was due to pill or arthritis, the purple gradually disappeared. 2)Right now I have a fading (Ihope) patch of thin-shiney-red skin obove my left ankle. It has been there for years but suddenly got worse about a year ago. My family dr tried this and that and finally a 6 month wait for a dermatologist. Who said a)a name I cant'd remember b)Poor circulation. Very likely due to Parkinson's affecting the set ofmuscles that push blood up the legs. c)that is how those hard to heal leg ulcers can start. d) elevate /exercise/ steroid creme/ and a call back to his leg clinic. 3) A third type of red patch bothered a friend. They were small nasty looking patches on his forehead due to excessively oily scalp. Again Parkison related. Hope this helps. Anne Rutherford Newfoundland