My husband has PD - 32/4 - symptomatic 14. He is on Sinemet 25/100 4x's/day and 5mg of Eldepryl 1x/day. I too have seen postings about "too much sinemet" and mortality due to Eldepryl - could someone please explain this to me also. It does seem cause for concern. Kevin is doing extremely well on this combination and don't want it change it unless absolutely necessary. Thanks much, Denise