Hello, All:
Further information on the autonomic functions of hot flashes, drenching
sweats, shallow breathing, etc..
Date: Fri, 1 Mar 1996 08:25:02 EST
From: [log in to unmask]
Subject: sweating
To Norm Archer: The question re. sweating is treated in an article
in the 4th quarter, 1995, issue of the NPF Parkinson's Report, which
is excerpted as follows:
Thermoregulation Abnormalities.
Impaired thermoregulatory control has long been known to occur in
patients with untreated idiopathic Parkinson's disease. Sudden periodic
episodes characterized by generalized and profuse hyperhidrosis
(excessive sweating) which appear to be independent from environmental
temperature influences during "off" periods. A similar phenomenon termed
sweating crisis had been observed during the early part of the century.
These events are often associated with other features of autonomic hyper-
activity such as hypertension, tachycardia, and flushing. Levodopa and
dopamine agonists improve these symptoms. Beta-blockers (propanolol)
may be beneficial. Other neurologic conditions where excessive sweating
has been described include diabetic neuropathy and familiar dysauto-
nomia. Peak-dose sweating, hyperplexia, and hyperthermia have also
been reported. Search for an alternative diagnosis in these situations
such as endocrine dysfunction or infection should be carried out. The
cause is poorly understood.
I hope this helps. Gaylord Rough <[log in to unmask]
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Document: 1
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Record from database: MEDLINE
Title:Drenching sweats as an off phenomenon in Parkinson's disease:
treatment and rela tion to plasma levodopa profile.
Author: Sage JI, Mark MH
Address
Department of Neurology, University of Medicine and Dentistry of New
Jersey-R obert Wood Johnson Medical School, New Brunswick 08903.
Source:Ann Neurol, 37: 1, 1995 Jan, 120-2
Abstract
We followed 4 patients with Parkinson's disease and severe,
intermittent, dre nching sweats. One patient was studied with serial
plasma levodopa levels and simultaneous clinical examinations. She was
observed during a severe sweating episode; this was associated with
subtherapeutic plasma levodopa levels (low dopa state). All 4
patients' sweats responded favorably to the institution of agonist
therapy. Drenching sweats should be considered part of the spectrum of
off-period levodopa-related fluctuations in Parkinson's disease.
Language of Publication
English
Unique Identifier
95118023
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Document: 2
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Record from database: MEDLINE
Title: Sweat function in Parkinson's disease.
Author: Mano Y; Nakamuro T; Takayanagi T; Mayer RF
Address: Department of Neurology, Nara Medical University, Japan.
Source:J Neurol, 241: 10, 1994 Oct, 573-6
Abstract
Sweat function was studied in patients with Parkinson's disease and in
normal adults by sympathetic skin response, the bromphenol blue
printing method and the silicone mould method. In patients with
Parkinson's disease, dysfunction of sweating was classified into two
types: one type involved the postganglionic fibres and the other
involved the preganglionic fibres or the central nervous system. The
latter was observed in patients with milder disease and the former was
observed in patients with severe disease. The progressive involvement
of sweat function in Parkinson's disease may reflect spread from the
central nervous system or preganglionic fibres to postganglionic
fibres. In a few patients the results of sweat tests were normal.
Ceruletide increased sweating in Parkinson's disease patients, and
decreased the prolonged latency of the sympathetic skin response. It
is hypothesized that ceruletide facilitates the preserved
somatosympathetic reflex of sweating.
Language of Publication
English
Unique Identifier
95138745
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Document: 3
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Record from database: MEDLINE
Title: Barium stone impaction in parkinsonism.
Author: Erhan Y; Koyuncu A; Osmanoglu N
Address:
Department of Surgery of Gastroenterology, Aegean University Medical
School, Izmir, Turkey.
Source: JPMA J Pak Med Assoc, 45: 6, 1995 Jun, 165-7
Abstract
Autonomic symptoms such as orthostatic hypotension, abnormal sweating
and constipation occur frequently in Parkinson's disease. In our case,
barium meal used for upper gastrointestinal study caused barium stone
formation and a paralytic-ileus-like syndrome. Therefore, attention
should be paid while using barium meal for diagnostic purpose in
Parkinsonism.
Language of Publication
English
Unique Identifier
96019639
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