Hello Bob I started my L>S> last November. 10 25/100 into 1000cc of O>J> 16 hourly doses of 60cc (if you find that the straight OJ is to acidic (some brands more than others) swig some Mylanta twice a day. I tried to cut it with 1/3 water but it is not so effective. Hope it works for you as it does for me. Joyce