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I spoke with Tony Schoonenberg of Loma Linda University Med Center's Movement Disorder Team (Dr. Robert Iacono) yesterday and per Tony, we can rule out Loma Linda as a trial site for Amgen. Also spoke to Amgen, in Newbury Park/Thousand Oaks (in the Conejo Valley, outside of Los Angeles), and they said they have trial sites all over the USA, with LOOOOONG waiting lists of folks eager to participate in the drug trials. Plus it DOES help if one has had a pallidotomy. (at this point in my text, read the rest of this statement as pure conjecture ----> Apparently that's where and how they get the new drug into the brain area, since it cannot get past the brain barrier by any other method. And so it goes..... Barb Mallut, [log in to unmask] ---------- From: PARKINSN: Parkinson's Disease - Information Exchange Network on behalf of Richard Fallon Sent: Thursday, August 15, 1996 2:20 PM To: Multiple recipients of list PARKINSN Subject: AMGEN STUDY of GDNF I called AMGEN to find out where they are performing their human trials of GDNF which was promising in helping relieve some of the symptoms (slowness, stiffness,rigidity)of PD in tests on primates. They will not release that information, however, they said that they are being held at centers that specialize in pallidotomies. Write-up available in NATURE 3/21/96 issue Vol. 380 pg. 255 for those interested. Anyone with further information on the AMGEN trials, please post. Father-in-law (81) has been fighting PD for 12 years. Thanks, Richard Fagin