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Gordon had a work-up three weeks ago at Oregon Medical School, Dr. John Nutt, their Head of Movement Disorders Clinic. His suggestion was amazing. Take Tums with each dose of Sinemet. Gordon now takes them with the Sinemet on top and chews them both. This has helped him. The idea, Said Dr. Nutt, is that Tums enhances medication. His afternoons have been better. A friend whosxe husband has kidney problems is doing the same thing and they feel it helps him (his Doctor's advice). Good Luck.