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you are the first person I have encountered who is on Trazadone. Wow, you meet all kinds of people here don't you? I take about 25 mg of Trazadone at bedtime each night, and although it doesn't do much (noticeably) for my mood, it sure helps me sleep, sometimes giving me silly dreams. I'm also on amantadine, and have been unaware of any adverse interaction between these two drugs, I'm not sure about the others. Jacob